Improvement of E Se tea extracts on renal mesangial cell apoptosis and high-fat-diet/streptozotocin-induced diabetic nephropathy

Journal of Functional Foods(2021)

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摘要
•E Se tea inhibited oxidative stress-induced mesangial cell apoptosis.•E Se tea achieved the protective effects through mitochondrial/caspase pathway.•E Se tea improved high-fat-diet/streptozotocin-induced diabetic nephropathy rats.•E Se tea decreased activation of renal caspase 3 on diabetic nephropathy rat.
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关键词
E Se tea, Malus toringoides (Rehd.) Hughes,Diabetic nephropathy,Apoptosis,Oxidative stress,HBZY-1,Caspase 3/9
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