Immunocyte Single Cell Analysis Of Vaccine-Induced Narcolepsy

Alexander Lind,Falastin Salami,Anne-Marie Landtblom,Lars Palm,Ake Lernmark,Jorgen Adolfsson,Helena Elding Larsson

EUROPEAN JOURNAL OF IMMUNOLOGY（2021）

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摘要

Increased incidence of narcolepsy type 1 (NT1) was observed following Pandemrix®-vaccination, initiated as a preventive measure against the 2009 Influenza pandemic. Here, single cell analysis was conducted to suggest a lower number of CD8 CD27 T cells among these patients. These findings provide understanding into the autoimmune pathogenesis of NT1.

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关键词

autoimmunity, narcolepsy, mass cytometry, vaccine, single cell analysis

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