Two New Luminescent Cd(Ii) Coordination Polymers And Their Application Values On Children Bronchopneumonia

Two Cd(II) coordination polymers namely, [Cd(L)(phen)(H2O)](n) (1) and [Cd(L)(bpe)(0.5)](n) (2) (H2L is 4,4'-{[1,2-phenylenebis-(methylene)]}bis(oxy)dibenzoic acid, bpe is 1,2-bis(-4-pyridyl) ethane and phen is 1,10-phenanthroline), have been created by the mixed-ligand self-assembly strategy. Moreover, the two compounds' luminescent and photocatalytic performances were also studied. The treatment activity and nursing application values on children bronchopneumonia was explored and specific mechanism was investigated simultaneously. First of all, the ELISA detection kit was implemented to detect the TNF-alpha and IL-6 levels released into the respiratory secretions after treatment of compound. Furthermore, the real time RT-PCR was conducted to determine the activation levels of NF-Kb signaling pathway in the airway epithelial cells. Finally, the cytotoxicity of the coordination polymers on normal airway epithelial cells was assessed through the CCK-8 assay. (C) 2021 The Authors. Published by Elsevier B.V. on behalf of King Saud University.