Higher Angiotensin Ii Type 1 Receptor (At1r) Levels And Activity In The Postmortem Brains Of Older Persons With Alzheimer'S Disease

C. Cosarderelioglu,C. George,R. Marx-Rattner,Q. Xue,J. Tian,E. Oh,L. Ferrucci,D. Bennett,J. Walston,P. Abadir

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY（2021）

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摘要

This study highlights molecular changes in b-RAS and offers insight into the association of these changes with brain pathology in AD. These findings can be important in shedding light on the benefits of RAS-modulating drugs in AD.

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