Terpenoids From Cameroonian Oxystigma Mannii (Baill.) Harms

J. H. Peyeino,G. B. Tabekoueng, H. L. M. Djomkam,M. K. Langat,N. Sadgrove,T. Prescott,H. Siddique,E. Mas-Claret,M. S. Isyaka,J. D. Wansi, J. C. Vardamides, A. F. K. Waffo

SCIENTIFIC AFRICAN(2021)

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摘要
We describe two new terpenoids, 3 '',5 ''-dihydroxycinnamoy1-beta, 28,30-dihydroxylup20(29)-ene (1) and 6S,9S-dihydroxycasbe-3E,7E,11E-trien-5,10-dione (2) and ten known asperglaucide, aridanin, isoscopoletin, maslinic acid, ursolic acid, oleanolic acid, lupeol, sitosterol, stigmasterol and stigmasterol-glucoside from a West African, GuineoCongolian mangrove and strand forest tree, Oxystigma mannii (Baill.) Harms. The structures of the new compounds were determined based on their 1D and 2D NMR, HRMS and FTIR. DP4+ probabilities were used to assign the configurations for compound 2. The two compounds were tested for their antimicrobial effects against Saccharomyces cerevisiae (BY4743), Escherichia coli (BW25113) and Bacillus subtilis (BY4743), but no inhibition was observed at the maximum concentrations tested (800 mu M). (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of African Institute of Mathematical Sciences / Next Einstein Initiative.
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关键词
Terpenoids, Casbane, Lupane, Antimicrobial activity, DP4(+)
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