Trends In The Influence Of Gender, Race, And Ethnicity On The Prevalence Of Kidney Stones: A Multi-Institutional And Claims Analysis

You have accessJournal of UrologyStone Disease: Epidemiology & Evaluation II (MP54)1 Sep 2021MP54-09 TRENDS IN THE INFLUENCE OF GENDER, RACE, AND ETHNICITY ON THE PREVALENCE OF KIDNEY STONES: A MULTI-INSTITUTIONAL AND CLAIMS ANALYSIS Joseph Crivelli, Naim Maalouf, Phyllis Yan, Amy Hughes, Ryan Hsi, Noah Canvasser, Naveen Kachroo, David Leavitt, Kyle Wood, Gabriela Oates, John Hollingsworth, and Dean Assimos Joseph CrivelliJoseph Crivelli More articles by this author , Naim MaaloufNaim Maalouf More articles by this author , Phyllis YanPhyllis Yan More articles by this author , Amy HughesAmy Hughes More articles by this author , Ryan HsiRyan Hsi More articles by this author , Noah CanvasserNoah Canvasser More articles by this author , Naveen KachrooNaveen Kachroo More articles by this author , David LeavittDavid Leavitt More articles by this author , Kyle WoodKyle Wood More articles by this author , Gabriela OatesGabriela Oates More articles by this author , John HollingsworthJohn Hollingsworth More articles by this author , and Dean AssimosDean Assimos More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002084.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Significant increases in kidney stone prevalence have been reported for Black and Hispanic individuals in the US, but the gender-specific contribution to this trend is unclear. We evaluated the distribution of prevalent stone disease by gender, race, and ethnicity in contemporary cohorts. METHODS: We identified patients with a kidney stone diagnosis between 2010-2019 from three centers (University of Alabama at Birmingham [UAB, n=32,745], University of Texas Southwestern [UTSW, n=51,354], and Parkland Memorial Hospital [PMH, n=22,967]). We also utilized a claims database (Optum Clinformatics Data Mart) to identify working-age adults with a kidney stone diagnosis from 2010-2019 (n=68,594). Differences in male-to-female ratio between groups across all datasets were assessed with the Mann-Whitney U test. In the Optum cohort, temporal trends in male-to-female ratio were modeled with linear regression. RESULTS: In each cohort, most Black stone formers were female, most White stone formers were male, and most non-Hispanic stone formers were male; in two of the four cohorts, most Hispanic stone formers were female (Figure 1). We observed a significant difference in male-to-female ratio between Black vs. White stone formers, but not between Hispanic vs. non-Hispanic stone formers (Figure 1). In the Optum cohort, a significant linear decline in male-to-female ratio was observed in White and non-Hispanic stone formers, but not in Black and Hispanic stone formers (Figure 2). CONCLUSIONS: An analysis of multi-institutional and claims data showed that most Black stone formers were female, whereas most White stone formers were male, demonstrating a significant difference in gender distribution. Based on insurance claims, the male-to-female ratio decreased in all groups over time, but most consistently among White and non-Hispanic patients. Further evaluation of these findings and their association with comorbidities and socioeconomic factors is needed to understand disparities in stone disease. Source of Funding: National Institutes of Health 1R01DK121709-01A1 © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e952-e952 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Joseph Crivelli More articles by this author Naim Maalouf More articles by this author Phyllis Yan More articles by this author Amy Hughes More articles by this author Ryan Hsi More articles by this author Noah Canvasser More articles by this author Naveen Kachroo More articles by this author David Leavitt More articles by this author Kyle Wood More articles by this author Gabriela Oates More articles by this author John Hollingsworth More articles by this author Dean Assimos More articles by this author Expand All Advertisement Loading ...