[( 1,3-Bis{2,6-Bis( Diphenylmethyl)-4-Methylphenyl} Imidazole2-Ylidene) Pdcl2( Net3)]: " Throwing Away" A Different Ancillary Ligand To Enhance The Catalytic Activity At Room Temperature

A considerable effort in ligand design for catalysis in recent years has led to remarkable achievements in cross-coupling reactions. In this work, we show that a careful selection of the ancillary ligands that complete the catalyst/precatalyst can provide an extra level of performance. Low loadings of [(IPr*)PdCl2(TEA)] {IPr* = 1,3-bis[2,6-bis(diphenylmethyl)-4-methylphenyl]imidazole-2-ylidene, TEA = triethylamine} catalyze the Buchwald-Hartwig amination reactions of aryl chlorides at room temperature in excellent yields, without the need for an inert atmosphere to set up or perform the reactions.