Clinical Efficacy And Nursing Experience Of Treating Pulmonary Tuberculosis With Levofloxacin Combined With Anti-Tuberculosis Drugs

Yan Liang, Xueqin Yang, Meifeng Liu, Yazhen Li,Y. Zhang

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES(2021)

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摘要
To observe the clinical efficacy of levofloxacin combined with anti-tuberculosis drugs in the treatment of pulmonary tuberculosis and explore effective nursing schemes. The 160 patients who had been clearly diagnosed with pulmonary tuberculosis in our hospital were selected as the study subjects. They were divided into study group and control group, each containing 80 cases. The control group was treated with pure anti-tuberculosis drugs, while the study group was treated with levofloxacin combined with other anti-tuberculosis drugs. In addition, the control group received general routine nursing, while the study group received comprehensive nursing. The treatment and nursing effects were compared between the two groups. The sputum tuberculomyces disappearance rate, cavity closing ratio, foci absorption rate and sputum tuberculomyces clearance time, cavity closing time, foci absorption time were 92.50 %, 97.50 %, 95.00 %, (5.34 +/- 1.29) mo, (5.31 +/- 1.20) mo, (5.03 +/- 1.65) mo in study group, while that values were 75.00 %, 80.00 %, 77.50 %, (7.80 +/- 2.16) mo, (7.69 +/- 2.21) mo, (7.59 +/- 2.39) mo in the control group. This indicates that indicators in study group were significant better than those in control group p<0.05. The incidence of adverse reactions (2.50 %) were lower in the study group than in the control group (15.00 %), p<0.05. The overall nursing satisfaction (97.50 %) was higher in the study group than in the control group (75.00 %), p<0.05. Good clinical efficacy can be achieved using levofloxacin combined anti-tuberculosis drugs in the treatment of pulmonary tuberculosis and combined use of comprehensive nursing intervention program can significantly improve treatment effect.
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关键词
Levofloxacin, anti-tuberculosis drugs, combination therapy, pulmonary tuberculosis, nursing intervention
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