A Case Study Of The Iodine-Mediated Cyclization Of C-2 '-Oh- And C-2-Oh-Chalcones Toward The Synthesis Of Flavones: Reinvestigation Of The Mechanisms

Synthesis of flavones from chalcones via the iodine-mediated cyclization required at least one hydroxy group at their C-2 '-positions. On the contrary, the ring oxidative cyclization from C-2-OH-chalcones under the same condition was unusual and reported only once. We evaluated the aforementioned method and found different results. The mechanisms in detail were discussed.