The phytochemical vitexin and syringic acid derived from foxtail fillet bran inhibit breast cancer cells proliferation via GRP78/SREBP-1/SCD1 signaling axis

Lichao Zhang,Xiaoqin La,Jinmiao Tian,Hanqing Li,Aiping Li, Yizhi Liu,Changxin Wu,Zhuoyu Li

Journal of Functional Foods（2021）

引用 7|浏览6

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摘要

•BPIS specifically inhibited breast cancer via blocking the conversion of SFA to MUFA.•VT and SA were the anti-breast cancer active ingredients of BPIS.•GRP78 was the target of VT and SA and mediated the conversion of SFA to MUFA.

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关键词

Foxtail millet,Vitexin,Syringic acid,GRP78,SCD1,Breast cancer

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