Cea-Rvmm Serotonergic Circuits And Sudden Unexpected Death In Epilepsy

Consensus exists on the importance of neural circuit in affecting the clinical outcome after sudden unexpected death in epilepsy (SUDEP). There is growing evidence that the serotonergic neuronal networks have a well-established role in SUDEP. Much progress has been made in our understanding of SUDEP since the seminal experiments of neural circuits. Future studies are that CeM-RVMM serotonergic circuits are poised to integrate multiple synaptic inputs from various sources thought to influence sudden unexpected death in epilepsy by melanocortinergic signaling.