Jiaji Acupoint Injection Of Salvia Miltiorrhiza-Extract Combined With Snb Affect Phn

Purpose: This study aims to investigate the effect of Jiaji-acupoint injection of Salvia Miltiorrhiza-extract combined with sympathetic nerve block in the treatment of Postherpetic Neuralgia (PHN). Methods: 80 patients with PHN were randomly divided into four groups: control group, nerve block group (NB), point injection group (PI), nerve block combined with point injection group (NB + PI), with 20 patients in each group. Patients NB + PI group received Jiaji-point injection of Salvia Miltiorrhiza-extract combined with sympathetic nerve block on the basis of medication. Results: Pain VAS significantly decreased at one week, three weeks and three months after treatment in all groups (P < 0.01). Compared with control group, Pain VAS in NB, PI, NB + PI group were significantly lower at one week, three weeks and three months after treatment (P < 0.01). However, the Pain VAS was significantly lower in NB + PI than that in the NB and PI group three months after treatment (P < 0.05). The effective rates were 80%, 95%, 95% and 100% in the control, NB, PI and NB + PI group three months after treatment, respectively. The effect in the NB + PI group was better than that in the control, NB and PI group (P < 0.05). CGRP decreased significantly three months after treatment in all groups (P < 0.01). CGRP in NB + PI group was the lowest among all the groups (P < 0.05). Conclusion: All those results indicate that Jiaji Acupoint injection of Salvia Miltiorrhiza-extract combined with SNB has the advantage of rapid onset, high effectiveness and best long-term effect in the treatment of PHN.