Nanoemulsions Containing Oil And Aqueous Extract Of Green Coffee Beans With Antioxidant And Antimicrobial Activities

E. B. Buzanello, G. T. B. Pinheiro Machado,S. Kuhnen, L. Mazzarino,M. Maraschin

NANO EXPRESS(2020)

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摘要
Coffee has bioactive compounds with protective effect against free radicals and antifungal and antibacterial activities that are beneficial to the health skin. This work aims to provide scientific evidence that nanoemulsions developed with oil and green coffee extract have antioxidant and antimicrobial effects. Nanoemulsions were prepared by spontaneous emulsification method using different concentrations of components (oil, extract and tensoactive) in order to optimize the preparation of formulations. The nanoemulsions presented globular morphology, negative charges, monodispersity and size around 200 nm. Two nanoemulsions, namely F7 and F16, presented characteristics of size and concentration of tensoactives more suitable for investigation regarding their antioxidant and antibacterial activities. The later assay was performed against standard strains of Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli at different nanoemulsion concentrations. The formulations proved to be inhibitors of free radicals and showed excelent antibacterial activity, demonstrating their potential for cosmetic and therapeutic applications.
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关键词
nanoemulsions, green coffee, antioxidant activity, antibacterial activity
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