Breast Fibromatosis: Radiologic-Pathologic Correlation And Review Of The Literature

Objective. - To review clinical and radiological aspects of an unusual lesion, mammary fibromatosis.Patients and methods. - We conducted a retrospective study of all cases diagnosed between 1993 and 2010, and reviewed all the clinical, radiological and pathological aspects of the lesions.Results. - Eleven cases, including nine women (one with bilateral fibromatosis) and one man, were identified. Patients were aged 21 to 78 and all presented with a palpable breast mass. In 50% of cases mammography detected the lesion, either as a spiculated mass (75%) or as a focal asymmetric density (25%). The lesion was always visible with sonography, and was usually (80%) suspicious. The lesion showed significant enhancement on CT or MRI in 83% of cases. The medium radiological size was 26 mm. Sonographically guided 14-gauge core needle biopsy suggested the diagnosis in all cases (5/5) and was able to assert it in three cases before excision. One recurrence was observed during the follow-up, which was of 3 to 8 years (medium follow-up 28 months).Conclusion. - Mammary fibromatosis often has a suspicious clinical and radiological appearance. Core biopsy is mandatory because it helps guiding the diagnosis before surgical excision. (C) 2012 Elsevier Masson SAS. All rights reserved.