Asymmetric Hydrogenation Of Benzalacetone Catalyzed By Rucl2(Tppts)(2)-(S,S)-Dpends In Water Medium

The asymmetric hydrogenation of benzalacetone catalyzed by ruthenium monophosphine complex RuCl2(TPPTS)(2) [TPPTS = P(m-C6H4SO3Na)(3)] modified by (S,S)-DPENDS (disodium salt of sulfonated (S,S)-1,2-dipheny1-1,2-ethylene-diamine) was investigated in a water medium. Under the optimized conditions, a chemoselectivity of 96.0% for 4-phenyl-3-butene-2-ol and ee value of 71.2% were obtained. The products could be easily obtained by simple extraction with n-hexane, and the catalyst could be reused five times without evident loss of catalytic activity and enantioselectivity.