Microsensor Systems For Environmental And Biomedical Analysis

Microsensors such as microelectrode array (MEA) and light-addressable potentiometric sensor (LAPS) have been widely used in environmental and biomedical field. In this chapter, the principle, fabrication and characterization of MEA and LAPS are introduced. For environmental application, an automatic analysis instrument for heavy metal detection is presented. Meanwhile, a project for in-situ and wireless monitoring is detailed. For biomedical application, cell-based biosensors using MEA and LAPS are popular. Microphysiometer monitoring the extracellular microenvironment has been commercialized. A cell physiological multi-parameter automatic analysis instrument for cell electric activity, morphology, and metabolic rates is also described.