Preparation And Photosynthesis-Inhibiting Activity Of 1-[(2-Nitrophenyl) Carbamoyl] Naphthalen-2-Yl Alkylcarbamates

20TH INTERNATIONAL ELECTRONIC CONFERENCE ON SYNTHETIC ORGANIC CHEMISTRY (ECSOC)(2016)

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摘要
In this study, a series of eight 1-[(2-nitrophenyl) carbamoyl] naphthalen-2-yl alkylcarbamates was prepared and characterized. The discussed compounds were prepared by microwave-assisted and conventional synthesis. The compounds were tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. The PET-inhibiting activity of the compounds was relatively low; the corresponding IC50 values ranged from 0.233 to 0.487 mmol/L and the highest activity within the series of compounds was observed for 1-[(2-nitrophenyl) carbamoyl] naphthalen-2-yl pentylcarbamate. The compounds were found to inhibit PET in photosystem II.
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关键词
Alkylcarbamates, Hydroxynaphthalene-carboxamides, PET inhibition, Spinach chloroplasts, Structure-activity relationships
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