Improving Crispr-Cas9 Activity And Specificity By Chemical Modification Of The Sgrna Backbone.

D. E. Ryan, D. Taussig,I. Steinfeld, S. M. Phadnis, B. D. Lunstad, M. Singh, X. Vuong, K. D. Okochi, R. Mccaffrey, M. Olesiak,S. Roy,C. W. Yung,B. Curry, J. R. Sampson, D. J. Dellinger,L. Bruhn

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL（2019）

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