LncRNA RBPMS-AS1 promotes NRGN transcription to enhance the radiosensitivity of glioblastoma through the microRNA-301a-3p/CAMTA1 axis

Wenyang Li,Yan Cui,Wenjia Ma,Ming Wang,Yang Cai,Yugang Jiang

Translational Oncology（2022）

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摘要

•RBPMS-AS1 and CAMTA1 are lowly expressed in GBM patients.•RBPMS-AS1 and CAMTA1 enhance the radiosensitivity of GBM.•miR-301a-3p diminishes the radiosensitivity of GBM.•RBPMS-AS1 enhances CAMTA1 expression in GBM cells through sponging miR-301a-3p.•CAMTA1 promotes NRGN transcription.

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关键词

Glioblastoma,LncRNA RBPMS-AS1,microRNA-301a-3p,CAMTA1,NRGN,Radiosensitivity

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