Hbot Combined With Sts Improves Hemodynamics And Hemorheology In Rvo Patients

Objective: This study was designed to analyze the effects of hyperbaric oxygen therapy (HBOT) combined with sodium tanshinone lla sulfonate (STS) in RVO (retinal vein occlusion) patients. Methods: 85 RVO patients admitted to our hospital from December 2017 to October 2018 were included, retrospectively analyzed, and randomly divided into the control group (CG, n=42) for HBOT and the observation group (OG, n=43) for HBOT combined with STS. The two groups were compared in terms of hemodynamics and hemorheology. Results: (1) At the end of, 1, 3, and 6 months after the treatment, the OG reported higher BCVA and lower CRT compared with the CG (P<0.05); (2) No significant differences were observed in the 2 groups in terms of intraocular pressure (IOP) before, at the end of, and at 1 week and 1 month after the treatment (P>0.05); (3) After the treatment, the whole blood viscosity (high/low shear rate), plasma specific viscosity, and fibrinogen levels were lower, and the RI, Vmax and Vmin were better in the OG compared with the CG (P<0.05); (4) After the treatment, the total effective rate was 90.70% in the OG and 73.81% in the CG (P<0.05). Conclusion: The combination of HBOT and STS improves the hemodynamics and hemorheology indices in RVO patients and is worthy of an extensive application in the future.