Gorham-Stout Syndrome - A Diagnostic And Therapeutic Challenge

Kristian Nikolaus Schneider,Christoph Theil,Georg Gosheger,Sebastian Klingebiel,Thomas Ackmann,Lukas Peter Lampe,Carolin Rickert,Dominik Schorn,Dimosthenis Andreou

OSTEOLOGIE（2020）

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摘要

Gorham-Stout syndrome (GSS) describes a pathophysiological idiopathic entity associated with osteolytic lesions and proliferation of blood- and lymph vessels. There are only around 300 reported cases of this rare, mono- or polyostostic condition in literature. This article presents the cases of two patients with GSS. Their respective medical histories with a delayed diagnosis of the disease, limited treatment options as well as treatment side-effects emphasise the complexity of diagnosis and treatment in GSS.

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关键词

Gorham-Stout Syndrom, vanishing bone disease, medical treatment, bisphosphonates, chylothorax, treatment side-effects

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