Ferritin Nanocages Can Deliver Inhibitors Of Hyperactive Protein Kinases For A Targeted Treatment Of Breast Cancer

Zuzana Skubalova,Zuzana Bytesnikova,Jan Pribyl,Akila Weerasekera

MENDELNET 2019: PROCEEDINGS OF 26TH INTERNATIONAL PHD STUDENTS CONFERENCE（2019）

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摘要

This project was focused on targeted chemotherapy based on ferritin nanocarriers with encapsulated various types of tyrosine kinase inhibitors. Then this nanoconstruct is surface-modified by folic acid, with the aim to achieve specific targeting to folate receptor overexpressed in targeted breast cancer cell line.

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关键词

encapsulation, ferritin, folic acid, nanoconstructs, specifically targeted therapy

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