Twisted Road To The Discovery Of Bms-986142: Using Conformationally Locked Atropisomers To Drive Potency In A Reversible Inhibitor Of Bruton'S Tyrosine Kinase (Btk) Scott Watterson , George De Lucca , Qing Shi , Charles Langevine , Qingjie Liu , Douglas Batt , Myra Beaudoin Bertrand , Hua Gong , Jun Dai , Henry Yip , Peng Li , Dawn Sun , Dauh-Rurng Wu , Chunlei Wang , Yingru Zhang , Sarah Traeger , Mark Pattoli , Stacey Skala , Lihong Cheng , Mary Obermeier , Rodney Vickery , Lorell Discenza , Celia D'Arienzo , Kathleen Gillooly , Tracy Taylor , Claudine Pulicicchio , Kim Mcintyre , Michael Galella , Andrew Tebben , Jodi Muckelbauer , Chiehying Chang , Luisa Salter-Cid , Joel Barrish , Percy Carter , Aberra Fura , James Burke , Joseph Tino ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2018）
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