Conventional T Cells And Non-Conventional T Cells During Mycobacterium Tuberculosis Infection. An Emerging Issue In Adult And Children Population

This paper focuses on cellular immune response to Mycobacterium tuberculosis according to our studies conducted at our laboratory in the last 20 years. T cells are critical components of the immune response to Mycobacterium tuberculosis. IFN-gamma is a key effector function of T cells during infection, but alone is not sufficient to control M. tuberculosis. The role of other T cells likely natural killer T cells and gamma delta T cells and/or different subset of monocytes-macrophages remark the role of no conventional T cells into control of Mycobacterium tuberculosis infection in different phase of the disease.