Effects Of Black Cohosh On The Plasminogen Activator System In Vascular Smooth Muscle Cells

H. G. Park,D-Y Lee,C-R Roh,Y-H Kang,D. Choi,B-K Yoon

18TH WORLD CONGRESS ON CONTROVERSIES IN OBSTETRICS, GYNECOLOGY & INFERTILITY (COGI)（2014）

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摘要

BcEx induces PAI-1 protein expression in the VSMCs likely via an oxidant mechanism. It also stimulates the enzyme activity of PAI-1 and reduces that of free t-PA. These findings suggest that black cohosh might exert a negative influence on fibrinolysis.

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关键词

Black cohosh,Plasminogen activator inhibitor 1,Vascular smooth muscle

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