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Stabilizing Inactive Conformations of MALT1 As an Effective Approach to Inhibit Its Protease Activity

Nicola Hughes,Paul Erbel,Frederic Bornancin,Christian Wiesmann,Nikolaus Schiering,Frederic Villard,Arnaud Decock,Bertran Rubi,Samu Melkko,Carsten Spanka,Nicole Buschmann,Carole Pissot-Soldermann,Oliver Simic, Rene Beerli,Mickael Sorge,Marina Tintelnot-Blomley,Karen Beltz,Catherine H. Regnier,Jean Quancard,Achim Schlapbach, Jean-Baptiste Langlois,Martin Renatus

Advanced Therapeutics（2020）

Cited 2|Views16
Key words
allosteric inhibition,crystallography,drug discovery,MALT1,NMR
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