Phantom Limb Rain Current And Emerging Treatments

Phantom limb pain (PLP) is a sensation of pain in an absent limb, often experienced as burning, throbbing, or lancinating pain or the feeling of pins and needles. Approximately 60% to 80% of amputees develop this debilitating condition, which is often misdiagnosed. Although the exact cause of PLP is poorly understood, theories suggest a multifactorial origin. While no clear-cut guidelines have been developed for the management and treatment of PLP, researchers have studied the use of anticonvulsants, antidepressants, anesthetics, N-methyl-D-aspartate receptor antagonists, and opioids. A number of nonpharmacologic and novel therapies have shown promise as well. As the number of amputees in the United States increases, it is important to become familiar with the various therapy options for PLP.