Review Of Nonneurogenic Overactive Bladder

Overactive bladder (OAB) disorder is a condition with a prevalence that increases with age. Frequently, patients afflicted with OAB experience symptoms of urinary incontinence, including increased urinary frequency and nocturia. Nonpharmacologic therapy such as behavioral therapy is considered first-line treatment, while second-line treatments include the use of antimuscarinic medications and the novel beta(3)-adrenergic agonist, mirabegron. These agents focus on associated symptoms of OAB to improve patients' quality of life by increasing the bladder's capacity and decreasing urinary bladder contraction. Pharmacists are essential in the management of OAB by providing education to patients and practitioners alike regarding key aspects of current treatment modalities that include, but are not limited to, adverse drug events, drug-drug interactions, and appropriate use of medications.