Spontaneous Intra Cerebral Haematoma After Precocious Fibrinolysis With Elevation Of Fibrinogen Degradation Products

BackgroundIntracerebral haematoma is considered as an essentially vascular disease related to the structure of vessels. A recent treatment, VII factor has indirectly shown the importance of haemostasis in this ailment.Objectiveexplored certain aspects of haemostasis in a series of intracerebral spontaneous haematomas.MethodHaemostasis tests have been achieved among patients with a spontaneous intracerebral haematoma. The rate of fibrinogen and fibrinogen degradation products (FDP) have been measured at the admission, while the count of thrombocyts, and INR and ACT have also been determined.ResultsThirteen successive patients have been studied. In three patients, an elevation of fibrinogen degradation factors has been observed (3/13 or 23%). A case of thrombopenia associated with the increase of FDP has been recorded.ConclusionIn a considerable subgroup of haematomas, one could observe a concomitant fibrinolysis during the first 24 hours. This phenomenon is either initial or secondary to a vascular rupture.