Primary Intraosseous Myxoid Chondrosarcoma Arising In The Right Radius

Aims: The aim of this study was to explore and analyze clinicopathological features, diagnosis, and differential diagnosis of primary intraosseous myxoid chondrosarcoma. Methods: A rare case of intraosseous myxoid chondrosarcoma was analyzed by histopathology, immunohistochemistry, and molecular pathology, combined with imaging. Related literature was comprehensively reviewed. Results: The patient was a 29-year-old young woman with a tumor located in the right forearm (10x6 cm). Imaging studies showed that the mid-right radius bone had expanded to a size of about 6.8x4.9x3.7 cm, with corresponding cortical thinning. Saw segmentation and enhanced scanning showed irregular enhancement, with the possibility of a low-grade malignant tumor on the right side of the middle radius. She underwent surgical resection. Histopathology, immunohistochemistry, and molecular pathology testing revealed intraosseous myxoid chondrosarcoma. Conclusion: Intraosseous myxoid chondrosarcoma is a rare soft tissue tumor. Diagnosis mainly relies on imaging, morphology, and immunohistochemical markers. If necessary, the line of molecular pathology is helpful, but the main treatment is surgical excision.