Primary Splenic Amyloidosis: A Case Report

Primary splenic amyloidosis (PSA) is an unusual disease, and it could perform as a kind of tumor. Moreover, the research on prognosis of the disease is poor. The etiology, epidemiology, clinical diagnosis and treatment of the disease remain challenging, because case reports of the disease are few in number. To the best of our knowledge, the majority of patients would survive well after the right treatment in accordance with other benign tumors. Here, we report a woman who had complained of upper left bellyache for 1 month and she was confirmed PSA by histology after splenectomy. Computed tomography showed enlargement of the spleen with multiple heterogeneous masses in the upper pole of the spleen. A laparoscopic splenectomy was performed which allowed histopathologic diagnosis. The patient was diagnosed with PSA, and survived for 16 months after surgery. Here, we have a brief discussion about the histopathological features, clinical behavior and treatment of PSA and review the relevant literature.