Chromatographic Study Of Protonation Of Purine Derivates

Petra Kristova, Blanka Hegrova,Premysl Lubal,Marta Farkova,Libuse Trnkova

X PRACOVNI SETKANI FYZIKALNICH CHEMIKU A ELECTROCHEMIKU/ 10TH WORKSHOP OF PHYSICAL CHEMISTS AND ELECTROCHEMISTS（2010）

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摘要

The correlation between retention behaviour of purine derivates and their structure was studied by RP HPLC system. The protonation constants were assessed from the retention characteristics. Influence of experimental conditions, such as buffer choice, salt concentration and methanol content in the mobile phase on the retention characteristics of analytes were examined.

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