Antibiotics Resistance And Effects On Atopic Dermatitis Of Skin Bacteria In 7a Military Hospital

Aim: This study aimed to identify the skin bacterial infection in atopic dermatitis patients treated at 7A Military Hospital, and evaluate the infection rate, effect on dermatitis conditions, and antibiotic resistance of S. aureus in the studied patients. The study was expected to serve as references for clinical activities in further researches of atopic dermatitis and related infections.Materials and Methods: This study employed the in-vitro experimental approach and convenience sampling. The total sample size comprised of 190 isolating samples from 190 patients. The severity of atopic dermatitis was assessed using the SCORAD index. Antibiotic susceptibility test followed the modified Kirby - Bauer method and the 2015 CLSI criteria. Data analysis was performed using the biological statistical algorithm with SPSS 16.0 software.Results: S. aureus accounted for 76.32% of all samples. The infection rate was higher in longer disease contract, presence of personal or family atopy, and higher recurrence, itchiness, and severity (p < 0.05). Resistance was high against clindamycin (77.2%) and erythromycin (76.6%), significant against cefoxitin (49.7%), and low against amikacin (4.1%).Discussion: The dominance of S. aurerus presence in the isolates and its role as both the cause and consequence of atopic dermatitis was well-known in the medical literature. Considerable cefoxitin resistance signified the presence of methicillin-resistant strain (MRSA), and the resistance against clindamycin and erythromycin was also reported in the literature. Amikacin still maintained its effectiveness and that was corresponding with other medical reports. S. aureus infection and relationship with atopic dermatitis were explainable by the medical literature. MRSA prevalence and resistance against clindamycin and erythromycin were alarming. Amikacin was still a viable treatment. Infection control, alternative treatments, and drug resistance monitors should be performed rigorously.