Multi-omics profiling of Earth’s biomes reveals that microbial and metabolite composition are shaped by the environment

biorxiv(2021)

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摘要
Using sequence data to understand function in microbial communities presents challenges, in part due to the complex intricacies of processes such as transcription and translation. Here, we sample the metabolome directly using untargeted metabolomics, and combine it with metagenomic sequencing to harness a multi-omics approach. We focus on a diverse sample set representing Earth’s habitats to describe the distribution of metabolites, and their relationships with microbial communities and the environment. ### Competing Interest Statement S.B. and K.D. are co-founders of Bright Giant GmbH.
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