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Preclinical Characterization and Target Validation of the Antimalarial Pantothenamide MMV693183

Laura E. de Vries,Patrick A. M. Jansen,Catalina Barcelo,Justin Munro,Julie M. J. Verhoef,Charisse Flerida A. Pasaje,Kelly Rubiano,Josefine Striepen,Nada Abla,Luuk Berning,Judith M. Bolscher,Claudia Demarta-Gatsi,Rob W. M. Henderson,Tonnie Huijs,Karin M. J. Koolen,Patrick K. Tumwebaze,Tomas Yeo,Anna C. C. Aguiar,Iñigo Angulo-Barturen,Alisje Churchyard,Jake Baum,Benigno Crespo Fernández,Aline Fuchs,Francisco-Javier Gamo,Rafael V. C. Guido,María Belén Jiménez-Diaz,Dhelio B. Pereira,Rosemary Rochford,Camille Roesch,Laura M. Sanz,Graham Trevitt,Benoit Witkowski,Sergio Wittlin,Roland A. Cooper,Philip J. Rosenthal,Robert W. Sauerwein,Joost Schalkwijk,Pedro H. H. Hermkens,Roger V. Bonnert,Brice Campo,David A. Fidock,Manuel Llinás,Jacquin C. Niles,Taco W. A. Kooij,Koen J. Dechering

Nature Communications（2022）

Cited 18|Views52
Key words
Antiparasitic agents,Drug development,Malaria,Mechanism of action,Molecular medicine,Science,Humanities and Social Sciences,multidisciplinary
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