Metaproteomic profiling of fungal gut colonization in gnotobiotic mice.

Veronika Kuchařová Pettersen,Antoine Dufour,Marie-Claire Arrieta

ANIMAL MICROBIOME（2022）

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摘要

We used quantitative proteomic profiling of gnotobiotic conditions to show how colonisation with selected fungal species impacts the host gut proteome. Our results suggest that an increased abundance of certain gut fungal species in early life may affect the developing intracellular attributes of epithelial and immune cells.

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关键词

Antimicrobials,Early life gut microbiome,Gnotobiotic murine model,Gut fungi,Metaproteomics,Quantitative Proteomics

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