Persistent bacterial coinfection of a COVID-19 patient caused by a genetically adapted Pseudomonas aeruginosa chronic colonizer
bioRxiv (Cold Spring Harbor Laboratory)(2020)
摘要
This study characterized a genetically adapted Pseudomonas aeruginosa small colony variant isolated from a COVID-19 patient who suffered persistent bacterial coinfection and eventually recovered from critical illness. Specification and modification of the isolates discovered at genomic and transcriptomic levels with aligned phenotypic observations indicated that these isolates formed excessive biofilm with elevated quorum sensing systems.
### Competing Interest Statement
The authors have declared no competing interest.
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关键词
persistent bacterial coinfection,<i>pseudomonas aeruginosa</i>
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