Quality-of-life impairment is not related to disease activity in lichen planopilaris and frontal fibrosing alopecia. Results of a preliminary cross-sectional study

Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are chronic lymphocytic cicatricial alopecias (CAs) with unclear etiopathogenesis. While LPP usually presents as inflamed and quickly progressing lesions over the vertex, FFA tends to affect primarily women as a slowly progressive frontotemporal alopecia. Both diseases can be associated with certain nonscalp lesions that may even precede the scalp lesions, and be very distressing, leading to impaired self-esteem and quality of life (QoL). We aimed to assess the relationship between QoL, signs and symptoms of inflammation, and associated nonscalp lesions in LPP and FFA.