The Existence and Regression of Persistent Bergmeister's Papilla in Myopic Children Are Associated With Axial Length

Purpose: The purpose of this study was to evaluate the existence and regression of persistent Bergmeister's papilla (PBP) in myopic eyes and determine its independent predictors. Methods: This cross-sectional population-based study included 472 eyes of 236 myopic children. PBPs were identified with swept-source optical coherence tomography (OCT) and were classified into three types (types I, II, and III) according to their morphologic features. Results: The mean patient age was 12.13 +/- 2.60 years (range = 5-18 years), and 118 (50%) participants were boys. The prevalence of PBPs in our study was 67.8% (160/236). There were significant differences in height, spherical equivalent (SE), and axial length (AL) between the PBP and non-PBP groups (P < 0.05). Type I PBP was noted in 173 eyes (66.8%); type II PBP in 59 eyes (22.8%); and type III PBP in 27 eyes (10.4%). The three PBP types showed significant differences in height, AL, and SE (P < 0.001). Stepwise linear regression analysis indicated that the height (B = 4.497, P < 0.001), PBP existence or not (B = -1.434, P < 0.001), and the types of PBP (B = 0.566, P = 0.041) was an independent predictor for AL, respectively. PBP was detected more frequently in the nasal quadrant than in the inferior quadrant of the disc. Conclusions: PBP regression was closely related to the AL and could be used as a new biomarker to indicate the progression of myopia. Translational Relevance: Our analysis of the presence and morphology of PBP might enable clinicians to judge the progression of myopia.