Two new lanostane-type triterpenoids from the fungus Periconia sp. TJ403-rc01.

The endophytic fungus sp. TJ403-rc01 (Dematiaceae) isolated from the leaves of Jacq. (Rosaceae) was cultivated on rice medium and chemically investigated, affording two new lanostane-type triterpenoids, namely pericinones A and B ( and ). Their structures were determined mainly by 1 D and 2 D NMR and HRESIMS data. Notably, it is the first report of lanostane-type triterpenoids from species of . Compounds and showed moderate anti-inflammatory activity against the NO production with IC values of 24.12 ± 0.73 and 11.38 ± 1.56 M, respectively.