Predictive roles of brain-derived neurotrophic factor Val66Met polymorphism on antidepressant efficacy of different forms of prefrontal brain stimulation monotherapy: A randomized, double-blind, sham-controlled study

Chih-Ming Cheng,Chen-Jee Hong,Hui-Ching Lin, Po-Jui Chu,Mu-Hong Chen,Pei-Chi Tu,Ya-Mei Bai,Wen-Han Chang,Chi-Hung Juan,Wei-Chen Lin,Shih-Jen Tsai,Tung-Ping Su,Cheng-Ta Li

Journal of Affective Disorders（2022）

引用 9|浏览16

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摘要

•BDNF genotypes may influence the efficacy of different prefrontal stimulations.•PiTBS delivers the consistent antidepressant efficacy across BDNF genotypes.•HF-rTMS exhibits different efficacy based on different BDNF genotypes.

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关键词

BDNF polymorphism,Val66Met,Antidepressant efficacy,Prolonged intermittent theta-burst stimulation,Repetitive transcranial magnetic stimulation

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