Angiopoietin-like protein 2 deficiency promotes periodontal inflammation and alveolar bone loss.

Chenxi Jiang,Siqi Yao,Yi Guo,Li Ma,Xiaoxuan Wang,Yuan Chen,Huihui Zhang,Zhengguo Cao

Journal of periodontology（2022）

引用 3|浏览14

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摘要

Our study provides the first evidence of an anti-inflammatory effect of ANGPTL2 in murine periodontitis. The findings demonstrate the critical and protective role of ANGPTL2 in alveolar bone loss and periodontal inflammation.

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关键词

ANGPTL2,alveolar bone loss,cell signaling,matrix metalloproteinases,periodontal ligament cells,periodontitis

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