BEAN'S SYNDROME (BLUE RUBBER BLEB NEVUS SYNDROME - BRBNS) AS A GASTROINTESTINAL BLEEDING - CASE REPORT AND REVIEW OF THE LITERATURE

BRBNS is a rare syndrome of vascular malformations caused by the TEK mutation associated with numerous lesions of the skin and gastrointestinal tract. We pres-ent a case report of 41 year old man with severe anemia with recurrent bleedings. The detailed clinical, endoscopical and histopathological description is given as a wide range of differential diagnosis of vascular lesions based on pathophysiology and updated classification of vascular lesions. Clinicopathological diagnosis and treatment options of BRBNS are discussed.