In-vivo evidence of systemic endothelial vascular dysfunction in COVID-19

•Endothelium-mediated vasodilator function is markedly reduced in COVID-19 post-infection stage compared to active infection and controls.•These findings suggest that endothelial vascular dysfunction may be a chronic complication of the SARS-CoV-2 infection.•This study opens new venues to investigate the clinical implication of vascular endothelial dysfunction in post-COVID syndrome using non-invasive techniques.