Deficiency of SREBP1c modulates autophagy mediated lipid droplet catabolism during oleic acid induced steatosis

Erdi Sozen,Tugce Demirel-Yalciner,Dyana Sari, Ceren Avcilar, Tuna Felix Samanci,Nesrin Kartal Ozer

Metabolism Open（2021）

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摘要

Our results implicate the effect of SREBP1c deficiency in modulating PPARα signaling and autophagy mediated LD catabolism against OA induced lipid accumulation.

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关键词

Lipid accumulation,SREBP1c,Autophagy,Non-alcoholic fatty liver disease

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