Submandibular Gland Transfer for the Prevention of Radiation Induced Xerostomia in Head and Neck Cancer - Dosimetric Impact With Intensity Modulated Radiotherapy.

SMG mean dose was lower by ∼2 Gy in TCPs relative to the non-transferred SMG mean dose in reoptimized NPs, although this difference did not reach statistical significance. Inverse planning likely decreases the benefit of SMG transfer to reduce the risk of xerostomia. More investigation is needed to evaluate if patient subsets would benefit more than others based on tumor location (tongue base versus tonsil) and treatment modality (proton versus photon).