The Correlation Between Changes in Cardiac Biomarkers and Cardiac Events in Patients With Non-Small Cell Lung Cancer (NSCLC) Treated With Stereotactic Body Radiation Therapy (SBRT)-Exploratory Analysis of a Phase II Study

A F Shepherd,A Yu, C A Margaret,R F Rhyne, G Barnes, C Peters,D McKnight, M Offin,A Schmitt, D Gelblum, N Shaverdian, A J Wu,D R Gomez, A Rimner,C B Simone Ii

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS(2021)

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摘要
Our results from this exploratory prospective analysis demonstrate a significant correlation between an increase in CRS during SBRT and the development of CVE in follow-up after SBRT. Additionally, a trend in association between an increase in CRS during SBRT and MHD was identified, which could indicate an underlying relationship between CRS change during RT and MHD. These findings should be further explored in a larger patient population.
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