Frameless Mlc-Based Radiosurgical Thalamotomies On The Modern Linear Accelerator Platform - Prospective Phase I/Ii Clinical Trial Results

Evan Thomas,Erik Middlebrooks,Richard Popple,Harrison Walker, Anthony Nicholas, Benjamin Mccullough,Natividad Stover, Julianna Coleman,Victor Sung,David Standaert,Barton Guthrie,Markus Bredel

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS（2021）

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摘要

Frameless, coneless MLC-based SRS thalamotomy on the LINAC is a safe, effective treatment. Proper implementation requires attentive involvement by an experienced movement disorder radiosurgery team. Data continue to mature, but current results anticipate congruence to historical GK controls. We have expanded the trial to allow 20 additional patients.

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