Longitudinal clinical and functional outcome in distinct cognitive subgroups of first-episode psychosis: a cluster analysis.

Priscilla P Oomen,Marieke J H Begemann,Bodyl A Brand,Lieuwe de Haan,Wim Veling,Sanne Koops,Jim van Os,Filip Smit,P Roberto Bakker,Nico van Beveren,Nynke Boonstra,Sinan Gülöksüz,Martijn Kikkert,Joran Lokkerbol,Machteld Marcelis,Bram-Sieben Rosema,Franciska de Beer,Shiral S Gangadin,Chris N W Geraets, Erna van 't Hag,Yudith Haveman,Inge van der Heijden,Alban E Voppel, Elske Willemse,Therese van Amelsvoort,Maarten Bak,Albert Batalla,Agaath Been, Marinte van den Bosch,Truus van den Brink,Gunnar Faber,Koen P Grootens, Martin de Jonge, Rikus Knegtering,Jörg Kurkamp, Amrita Mahabir,Gerdina H M Pijnenborg,Tonnie Staring,Natalie Veen,Selene Veerman,Sybren Wiersma, Ellen Graveland, Joelle Hoornaar,Iris E C Sommer

Psychological medicine（2021）

引用 12|浏览35

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摘要

Current results demonstrate the existence of three distinct cognitive subgroups, corresponding with clinical outcome at baseline, 6- and 12-month follow-up. Importantly, the cognitively preserved subgroup was larger than the severely impaired group. Early identification of discrete cognitive profiles can offer valuable information about the clinical outcome but may not be relevant in predicting self-reported functional outcomes.

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关键词

Clustering,FEP,cognition,functional outcome,global functioning,psychosis

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