Follow-up Reader Response: Intravenous Immunoglobulin Therapy in Patients With Painful Idiopathic Small Fiber Neuropathy

We thank Dr. Faber and colleagues for their reply. We agree that intravenous immunoglobulin therapy (IVIG) is not a remedy for all patients with idiopathic small fiber neuropathy (I-SFN). However, the study population was nonrepresentative of clinical practice, given the 75% screening exclusion of patients with SFN. Furthermore, the clinical relevance is limited because the reasons for exclusion were not provided, other than the 16% exclusion for autoimmune comorbidities.1 These are precisely the patients who should be considered for immunotherapy.2